{"id":3944,"date":"2021-12-02T09:05:08","date_gmt":"2021-12-02T08:05:08","guid":{"rendered":"https:\/\/aa-pnh.pe-dev.de\/glossar\/hla-system\/"},"modified":"2021-12-02T09:06:18","modified_gmt":"2021-12-02T08:06:18","slug":"hla-system","status":"publish","type":"glossary","link":"https:\/\/aa-pnh.org\/en\/glossar\/hla-system\/","title":{"rendered":"HLA system"},"content":{"rendered":"<p>An important regulatory system for the organism&rsquo;s immune defences. <a class=\"glossaryLink\" aria-describedby=\"tt\" data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;HLA typing&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;Examination of HLA characteristics A, B, C, DRB1 and DQB1 for stem cell transplantation&lt;\/div&gt;\" href=\"https:\/\/aa-pnh.org\/en\/glossar\/hla-typing\/\" data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex=\"0\" role=\"link\">HLA typing<\/a> is extremely important in preparation for allogenic transplantation. The more similar the <a class=\"glossaryLink\" aria-describedby=\"tt\" data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;HLA system&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;An important regulatory system for the organism&amp;#039;s immune defences. HLA typing is extremely important in preparation for allogenic transplantation. The more similar the HLA systems of donor and recipient, the lower the risk of transplant rejection and GvHD and the greater the chance of(...)&lt;\/div&gt;\" href=\"https:\/\/aa-pnh.org\/en\/glossar\/hla-system\/\" data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex=\"0\" role=\"link\">HLA system<\/a>s of donor and recipient, the lower the risk of transplant rejection and <a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;GvHD&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;GvHD; graft versus recipient response. The donor&amp;#039;s immune system transplanted with a foreign donation (e.g. stem cells) can recognise the recipient&amp;#039;s body cells as foreign and attack them. A distinction is made between acute GvHD (grades 1-4) and chronic GvHD (limited and extensive form). The(...)&lt;\/div&gt;\"  href=\"https:\/\/aa-pnh.org\/en\/glossar\/gvhd\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'  tabindex='0' role='link'>GvHD<\/a> and the greater the chance of successful allogeneic stem cell transplantation.  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>An important regulatory system for the organism&rsquo;s immune defences. <a class=\"glossaryLink\" aria-describedby=\"tt\" data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;HLA typing&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;Examination of HLA characteristics A, B, C, DRB1 and DQB1 for stem cell transplantation&lt;\/div&gt;\" href=\"https:\/\/aa-pnh.org\/en\/glossar\/hla-typing\/\" data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex=\"0\" role=\"link\">HLA typing<\/a> is extremely important in preparation for allogenic transplantation. The more similar the <a class=\"glossaryLink\" aria-describedby=\"tt\" data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;HLA system&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;An important regulatory system for the organism&amp;#039;s immune defences. HLA typing is extremely important in preparation for allogenic transplantation. The more similar the HLA systems of donor and recipient, the lower the risk of transplant rejection and GvHD and the greater the chance of(...)&lt;\/div&gt;\" href=\"https:\/\/aa-pnh.org\/en\/glossar\/hla-system\/\" data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex=\"0\" role=\"link\">HLA system<\/a>s of donor and recipient, the lower the risk of transplant rejection and <a class=\"glossaryLink\" aria-describedby=\"tt\" data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;GvHD&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;GvHD; graft versus recipient response. The donor&amp;#039;s immune system transplanted with a foreign donation (e.g. stem cells) can recognise the recipient&amp;#039;s body cells as foreign and attack them. A distinction is made between acute GvHD (grades 1-4) and chronic GvHD (limited and extensive form). The(...)&lt;\/div&gt;\" href=\"https:\/\/aa-pnh.org\/en\/glossar\/gvhd\/\" data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex=\"0\" role=\"link\">GvHD<\/a> and the greater the chance of successful&hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"menu_order":0,"template":"","meta":{"footnotes":""},"class_list":["post-3944","glossary","type-glossary","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/aa-pnh.org\/en\/wp-json\/wp\/v2\/glossary\/3944","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aa-pnh.org\/en\/wp-json\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/aa-pnh.org\/en\/wp-json\/wp\/v2\/types\/glossary"}],"author":[{"embeddable":true,"href":"https:\/\/aa-pnh.org\/en\/wp-json\/wp\/v2\/users\/3"}],"version-history":[{"count":0,"href":"https:\/\/aa-pnh.org\/en\/wp-json\/wp\/v2\/glossary\/3944\/revisions"}],"wp:attachment":[{"href":"https:\/\/aa-pnh.org\/en\/wp-json\/wp\/v2\/media?parent=3944"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}