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Vaccination, vaccination, vaccination – there are few other topics that dominate the media, politics, but also our conversations with family and friends so much at the moment: Rightly, because the development of vaccines against the coronavirus and the increasing “vaccination coverage”<\/strong> of the population feed the hope of overcoming this crisis at some point.<\/p>\n For a few months, however, there have been indication<\/a>s that the corona vaccination does not work equally well for all people: A study from March of this year found that people taking immunosuppressive<\/a> therapy are less able to develop protection against<\/strong> a COVID-19 infection than people without this medication. This can be easily explained: In search of a solution to this problem, a study published in June 2021 can give reason for cautious optimism: A third dose<\/strong> of a COVID vaccine resulted in one in patients who were taking immunosuppressive<\/a> drugs as a result of a previous organ transplant Increase in antibody<\/a> levels against the coronavirus. The validity of the study is limited, however, as only a few patients (30) took part and were not vaccinated with a standardized vaccine.<\/p>\n A larger study<\/strong> from France (published in July 2021) was carried out on 383 kidney transplant patients under immunosuppressive<\/a> therapy: In the blood test it was found that in 28% of the patients in whom no antibodies<\/strong> could be detected after two doses of the vaccine, this was<\/strong> done a third vaccination<\/strong> could be induced. In 82% of the patients, the immune response could be improved by a third dose.<\/p>\n Such studies have so far mainly been carried out on organ transplant patients. It is suspected, however, that the results in patients with other underlying diseases<\/strong> (such as AA) could be similar<\/strong> because the same or comparable immunosuppressive<\/a> drugs are involved. In Germany alone there are eleven medical centers that are currently researching this issue – so it can be assumed that further scientific results will be published in the next few months.<\/p>\n At the moment<\/strong> there are no guidelines or recommendations from<\/strong> the specialist societies and vaccination commissions regarding a third administration of the corona vaccine. However, the results of the studies mentioned give hope that there is also a chance in our patient group to increase the protection against corona with a third vaccination. We would be happy to keep you up to date on this topic. Stay healthy!<\/p>\n
\n The mRNA vaccines from Pfizer-BioNTech and Moderna used in the study normally elicit a response from the body’s own immune system<\/a>. This creates antibodies<\/strong> that the coronaviruses can fight off in the event of an infection. However, if the immune system<\/a> is suppressed with medication, as can be necessary in many diseases – including AA – these antibodies can often not be formed or can be formed in smaller quantities and the risk that protection against COVID-19 fails is increased .<\/p>\n