vaccination

Update of PNH guideline

Photo: psdesign1_fotolia

 

Guidelines are summaries of the current scientific knowledge about a disease – in addition to a complete list of possible symptoms and the most targeted diagnostic methods, you can read about the best possible treatment options according to the current state of knowledge. They serve primarily as a non-binding guide for doctors, but also contain interesting information for patients. Every now and then, guidelines are updated so that the findings of new studies can be incorporated into everyday medical practice - this is exactly what happened this month for the PNH guideline of the German Society of Haematology and Medical Oncology (DGHO) . The last version was still from November 2019 and a revision was necessary in particular to bring recommendations on the use of new drug therapy options up to the status of 2022: Specifically, we are talking about pegcetacoplan, the new C3 complement inhibitor, which has been approved in the EU since December 2021 under the trade name Aspaveli® and, according to the manufacturer Swedish Orphan Biovitrum AB (Sobi), is expected to be available as a therapy option in Germany from April 2022. READ MORE

Recommendations regarding COVID-19 vaccination in AA/PNH updated

syringe with vials for vaccination © weyo

 

The SARS-CoV-2 pandemic continues to have us in its grip. Many AA/PNH patients are seeking advice on whether to get vaccinated (again) against the virus. Two of Germany's AA/PNH specialists, Dr Britta Höchsmann (UK Ulm) and Dr Jens Panse (UK Aachen), have analysed the scientific data available so far and updated their recommendations on vaccination. The two doctorsemphasise that their letter refelcts their personal recommendations and is not an official statement of the university hospitals or theDeutschen German Society of Haematologoy and Medical Oncology (DGHO). The letter should be understood as an aid until the statement of the DGHO expert group (non-malignant haematology working party) is available.

In general, Dr Höchsmann and Dr Panse consider the risk of infection with the SARS-CoV-2 ("Corona") virus to be more serious than the possible consequences of vaccination. The two experts emphasise that depending on the disease and status, some things should be taken into account, e.g. time of vaccination, type of vaccine etc.

For information is available in German in the recommendation letter regading COVID-19 vaccination in AA/PNH by Dr Höchsmann and Dr Panse.

Information on corona vaccination for aplastic anaemia

In a DGHO paper, Prof. Dr. Alexander Röth from the Essen University Hospital points out suspected cases in patients with aplastic anemia in connection with the SARS-CoV-2 ("Corona") vaccination. At the West German Tumor Center (WTZ), relapses of the disease (recurrences) have been observed in 3 patients after vaccination. In 3 other patients, the number of blood platelets (thrombocytes) continued to fall, and 2 patients received the initial diagnosis of aplastic anemia shortly after the vaccination. Patients with aplastic anemia should therefore consult their treating hematologist regarding (further) SARS-CoV-2 ("Corona") vaccinations. Download DGHO paper
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